![]() People who have Marfan syndrome can have weak tissue in their heart valves. An aortic dissection weakens the vessel's structure and can result in a rupture, which may be fatal. This can cause severe pain in the chest or back. Dissection occurs when a small tear in the innermost layer of the aorta's wall allows blood to squeeze between the inner and outer layers of the wall. The wall of the aorta is made up of layers. In people who have Marfan syndrome, this is most likely to happen at the aortic root - where the artery leaves your heart. The pressure of blood leaving your heart can cause the wall of your aorta to bulge out, like a weak spot in a tire. Faulty connective tissue can weaken the aorta - the large artery that arises from the heart and supplies blood to the body. The most dangerous complications of Marfan syndrome involve the heart and blood vessels. Marfan syndrome can interfere with the normal development of the ribs, which can cause the breastbone to either protrude or appear sunken into the chest.īecause Marfan syndrome can affect almost any part of your body, it may cause a wide variety of complications. If your doctor suspects a problem, you'll likely be referred to a specialist for further evaluation. If you think that you or your child may have Marfan syndrome, talk to your doctor or pediatrician. A high, arched palate and crowded teeth.A breastbone that protrudes outward or dips inward. ![]() Disproportionately long arms, legs and fingers.Some people experience only mild effects, but others develop life-threatening complications. The signs and symptoms of Marfan syndrome can vary greatly, even among members of the same family, because the disorder can affect so many different areas of the body. Your doctor may want to measure your arm span if he or she thinks you might have the disorder. Marfan syndrome is a genetic disorder that causes people to have unusually long arms, legs and fingers.
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